Remote companies headquartered in DE
5 companies headquartered in DE are in the RemoteWork directory. None of them has a live role on RemoteWork at the moment, but each company page tells you who to contact and what to say if you reach out anyway.
SaaS is the most common sector (2). Düsseldorf is the most common city (1).
1 of them hires from Nigeria or elsewhere in Africa. Headquarters is only where the company is registered; most of these hire remotely across time zones, so read each company page for where it actually hires.